GravitateBio · NECS Centenarian Proteomics · May 2026
Proteins elevated in people who lived to 100
33 proteins significantly elevated in New England Centenarian Study participants vs controls (adj p<0.05, ESM-2 transformer embeddings). Click any card to explore structure, function, and characteristics.
33
Elevated proteins
26
With PDB structures
24
Secreted / ECM
20
NECS cross-validated
78.8%
Absent from organ clocks
Category
ECM / Structural
Complement / Immune
Metabolic / Lipid
Protease inhibitor
Proteostasis
Other
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Protein characteristics
Molecular weight distribution and functional categories across the 33 centenarian-elevated proteins.